Search of the Limits of Hysteresis Interval in Time of Control Rhythm in Isolated Atrium by Delayed Feedback

Abstract

The adaptive rhythm control by delayed feedback we tested in rabbits isolated right atria in cases of various arrhythmias, on diapason 40−90 contractions/min, using the continually receiving information about the duration of latest contractions periods of atrium. In time of the descriptive experiment the hysteresis interval we determined using the gradually prolongation of the action potentials (AP) periods of atrium cells to the appearance of the spontaneous AP′s and this interval are calculated along the values of the spontaneous AP′s and along ruling stimulus serving moment together including and the complementary delay. Were established that the active search of the hysteresis interval in time of rhythm control by delayed feed-back, together with maintenance of the frequency of stimulus in possible limits, can to minimize the number of ruling stimulus. However, if the limits of hysteresis interval exceed the possible limits of the atrium contractions periods, the decreasing of number of stimulus are unsuccessful. Ill. 6, bibl. 8 (in Lithuanian; summaries in Lithuanian, English and Russian).