In Vivo Testing of the Semi-Closed Loop Infusion System: the Preliminary Observations

  • Audrius Andrijauskas Vilnius University Faculty of Medicine
  • Vytautas Markevicius Kaunas University of Technology
  • Dangirutis Navikas Kaunas University of Technology
  • Narunas Porvaneckas Vilnius University Faculty of Medicine
  • Darius Andriukaitis Kaunas University of Technology
  • Edgaras Stankevicius Lithuanian University of Health Sciences
  • Valentinas Uvarovas Vilnius University Faculty of Medicine
  • Jurate Sipylaite Vilnius University Faculty of Medicine
  • Giedrius Kvederas Vilnius University Faculty of Medicine
  • Giedrius Gelzinis Kaunas University of Technology
Keywords: Closed-loop, major orthopedic surgery, fluid infusion, decision support system, non-invasive haemoglobin, continuous non-invasive arterial pressure (CNAP).

Abstract

An In Silico testing of our novel automated clinical decision support system (ACDSS) in a prototype semi-closed loop (SCL) infusion system was previously reported. The decision making therein is based on the evaluation of hemodynamic and hemodilution parameters in compliance with an algorithm that implies interchangeable application of fluid infusion, vasopressor injection and red cell transfusion. Before starting the clinical validation trial, several amendments to the clinical algorithm were made on the basis of minor deficiencies revealed during an In Silico testing. For an intervention group in an on-going prospective randomised clinical trial, our prototype SCL infusion system is applied continuously for 12 perioperative hours in patients undergoing total hip replacement. This report describes our preliminary observations of the system’s performance in first 12 patients from an intervention group who completed the study.

DOI: http://dx.doi.org/10.5755/j01.eee.21.1.2458

Published
2015-04-01
How to Cite
Andrijauskas, A., Markevicius, V., Navikas, D., Porvaneckas, N., Andriukaitis, D., Stankevicius, E., Uvarovas, V., Sipylaite, J., Kvederas, G., & Gelzinis, G. (2015). In Vivo Testing of the Semi-Closed Loop Infusion System: the Preliminary Observations. Elektronika Ir Elektrotechnika, 21(1), 28-32. https://doi.org/10.5755/j01.eee.21.1.2458
Section
ELECTRONICS