Radiosensitized Treatment of Primary or Metastatical Malignant Brain Tumors with Hematoporphyrin Derivative

  • L. Bloznelytė-Plėšnienė Vilnius University
  • L. Rutkovskienė Vilnius University

Abstract

Human brain is not tolerant to amounts of gamma radiation up to 60 Gy that are typically used by traditional oncological radiation therapy. This amount can be considerably reduced if the gamma radiation is applied to malignant tumors sensibilized by a derivative of hematoporphyrin (HpD) Several important questions arise concerning this methodology: what is the optimal wavelength of ionizing radiation. What is an effective regime and dosage of radiation. Answers to these questions depend on the morphological type of the tumor. In the present study we refer to the results of the treatment of 48 patients with malignant brain tumors. Ill. 4, bibl. 15 (in English; summaries in English, Russian and Lithuanian).

Published
2015-03-19
Section
T 115 MEDICINE TECHNOLOGY